Dont expect to see these actors in a buddy comedy soon. For this list, well be looking at the most notable actors whose past experiences together (be it on a set or off) mean we probably wont be seeing them on screen at the same time ever again. Our countdown includes Bill Murray & Lucy Liu, Julia Roberts & Nick Nolte, Charlie Sheen & Selma Blair, and more! Which of these duos will YOU miss most on screen? Let us know in the comments!
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